Mariano Esteban and Juan García Arriaza’s project, CSIC-Biofabri, consists of using an inactivated virus of the smallpox family to transport and insert the Spike protein of SARS-CoV-2, thus allowing the virus to enter the cells. In this way human immunisation is achieved  by creating antibodies against the protein. This prototype has shown 100% efficiency in mice and will soon begin clinical phases. Biofabri is the joint sponsor and reponsible for developing the prototype for future testing on healthy volunteers.


Vicente Larraga’s vaccine project consists of placing a SARS-CoV-2  antigen gene in a DNA synthetic transporter (a plasmid) that can be inserted into the patient’s organism to induce protection against the infection. This project is at the preclinical phase in animal models

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